教育经历：
本硕博均毕业于伟德bv1946官网，博士期间获国家留学基金委资助赴加拿大滑铁卢大学进行联合培养，获湖南省优秀博士学位论文。
工作经历：历任伟德bv1946官网药剂学系主任，现任伟德bv1946官网副院长。
研究领域：新型药物制剂、皮肤医用医疗器械与化妆品研究
招生方向：药学（药剂学）；生物医药
社会兼职
任Exploration杂志科学编辑，Acta Pharm. Sin. B, Asian J. Pharm. Sci., Chin. Chem. Lett., Chin. J. Cancer Res.杂志青年编委，肿瘤药学杂志编委。任中国药学会药剂专委会青年委员，中国颗粒学会青年理事，湖南省肿瘤药物研究与转化专委会副主任委员，湖南省药学会药剂专委会委员。
人才项目及获奖：
湖南省科技人才托举工程，年轻优秀科技人才，湖南省科协，2020年
湖南省优秀青年基金，肿瘤药剂学，湖南省科技厅，2021年
湖湘青年英才，湖南省科技厅，2021年
医学学科青年骨干人才，湖南省卫生健康委，2023年
湖南省自然科学二等奖（排名第一）
指导大学生创新创业大赛国家级奖项6项，省级奖项5项（互联网+，挑战杯等）
科研成果：
Ø 主持科研项目：
纵向国家级项目
国家自然科学基金，可突破免疫屏障的“隐形”沙门氏菌联合放疗免疫增敏用于宫颈癌的治疗研究
国家自然科学基金，基于功能核酸串联的诊疗一体化探针的构建与应用研究
国家自然科学基金，以黑色素瘤外泌体高皮肤渗透及免疫调节作用为启发的抗银屑病仿生制剂研究
横向项目
校企合作科研项目20余项
Ø 授权发明专利：
以第一发明人授权国家发明专利13项，已完成转让专利10项，部分专利列举如下：
1. 纳米配位聚合物及其制备方法和应用，ZL 201910805848.4，排名第一，授权公告日：2020年06月23号
2. 一种抑制活化巨噬细胞增殖的聚合物/银活性键合物及其制备和应用，ZL 201910374069.3，排名第一，授权公告日：2020年06月16号
3. 一种酸性环境中可降解的表面涂层及其制备方法与应用，ZL 202010675017.2，排名第一，授权公告日：2021年04月13日
4. 一种电荷可控的聚合物材料及其制备方法与应用，ZL 202010676053.0，排名第一，授权公告日：2021年07月23日
5. 一种DNA/纳米复合物及其制备方法与应用，ZL 202110041560.1，排名第一，授权公告日：2022年06月28日
6. 包载甲氨蝶呤的铁-鞣酸配合物及其制备方法和应用，ZL202010903340.0，排名第一，授权公告日：2022年08月12日
7. 一种具有粘液渗透的核酸纳米载体及其制备方法与应用，ZL202111304068.5，排名第一，授权公告日：2022年11月25日
8. 雄黄纳米粒的制备方法和应用，ZL202010887138.3，排名第一，授权公告日：2022年11月25日
9. 一种多酚自聚纳米粒及其制备方法与应用，ZL 2021 1 1433444.0，排名第一，授权公告日：2024年05月03日
10. 一种基于 DNAzyme 调控基因编辑的方法，ZL 202111160432.5，排名第一，授权公告日：2022年03月04日
11. 一种用于靶向治疗血栓性疾病的纳米颗粒及其制备方法和应用，ZL 2023 1 0165897.2，排名第一，授权公告日：2024年06月18日
12. 核酸检测探针及其制备方法，排名第二，ZL 202110532356，授权公告日：2021-08-24
代表性论文
以（共同）通讯作者身份在Adv. Funct. Mater., ACS Nano, Adv. Sci.等国际权威期刊发表SCI论文100余篇，总被引7000余次，H指数50；高被引论文15篇，热点论文4篇；入选全球前2%顶尖科学家2023、2024年榜单，部分论文列举如下：
1. Yuanzheng Chen, Qubo Zhu, Yanbin Zhou, Wenhu Zhou*, Yan Chen*, Multifunctional nanomedicine targeting the 'seed-and-soil' of hair follicles via simultaneous alleviation of oxidative stress and activation of autophagy for androgenetic alopecia therapy, Materials Today Bio, 2025, 102145
2. Jiaojiao Zhu, Tiao Wen, Yunxiao Ma, Qingya Zeng, Yilan Lin, Yutian Liu, Shanshan Chen, Qiang Wang* and Wenhu Zhou*, Enhanced Xanthium-Inspired ZnO for Precision Antibacterial Therapy and Regeneration of Infected Wounds, Adv. Healthcare Mater, 2025, 2501009
3. Jiaojiao Zhu, Qingya Zeng, Yutian Liu, Yilan Lin, Ding Ma, Tiao Wen, Pei Li, and Wenhu Zhou*, Smart Nanosilver Strikes Twice: Precision Bacteria Killing Meets Autophagy-Boosted Healing for Infected Wounds, Adv. Funct. Mater., 2025, 2507797
4. Jiaojiao Zhu, Tiao Wen, Yunxiao Ma, Qingya Zeng, Pei Li and Wenhu Zhou*, Biomimetic Hyaluronic Acid-Stabilized Zinc Oxide Nanoparticles: Selective Antibacterial Activity and Multi-Mechanistic Skin Repair for Acne Treatment, Journal of Controlled Release, 2025, 382, 10, 113754
5. Qingya Zeng #, Jiaojiao Zhu #, Zongyun He, Hong Qin, Wenhu Zhou*, Fangqi Hua *, Jin Yang *, Context-dependent roles of 5-HT and its receptors in tumor growth and wound healing: Mechanisms and therapeutic implications, Chin J Cancer Res, 2025, 37, 2: 268-288
6. Jieru Yang#, Jiaojiao Zhu#, Shan Lu, Hong Qin, Wenhu Zhou*, Transdermal Psoriasis Treatment Inspired by Tumor Microenvironment-Mediated Immunomodulation and Advanced by Exosomal Engineering, Journal of Controlled Release, 2025, 382, 10, 113664
7. Hanane Aliouat, Detian Zhang, Lanyuan Peng, Jiaxin Huang, Hongshi Cheng, Jiaojiao Zhu, Xiang Chen, Nuli Xie*, Wenhu Zhou*, Shuang Zhao*, Targeted DNA Nanomachine Enables Specific miRNA-Responsive Singlet Oxygen Amplification for Precise Cutaneous Squamous Cancer Therapy, Adv. Sci. 2025, 12, 2415296
8. Jiaxin Huang, Jieru Yang, Yuanying Yang, Xiaofeng Lu, Juan Xu, Shan Lu, Hong Pan, Wenhu Zhou*, Wenqun Li*, Songwen Chen*, Mitigating Doxorubicin-Induced Cardiotoxicity and Enhancing Anti-Tumor Efficacy with a Metformin-Integrated Self-Assembled Nanomedicine, Adv. Sci. 2025, 2415227
9. Ying Yao, Yuanzheng Chen, Jie Fu, Jinsong Ding, Wenhu Zhou*, Xinyi Chen*, Xiuping Wan*, A metal-polyphenol network-based iron supplement with improved stability and reduced gastrointestinal toxicity for iron deficiency anemia therapy, Materials Today Bio, 2025, 31, 101598
10. Peng Liu+, Ming Zhou+, Zhisheng Luo, Lu Hao, Jessica C. Hsu, Weibo Cai, Wenhu Zhou*, Shuo Hu*, A 177Lu-nucleotide coordination polymer-incorporated thermosensitive hydrogel with anti-inflammatory and chondroprotective capabilities for osteoarthritis treatment, Biomaterials, 2025, 317, 123098
11. Xiangcheng Zhao+, Peng Yan+, Hailong Zhang, Wenhu Zhou*, Jinsong Ding*, A novel levodopa-carbidopa three-layer gastroretentive tablet for improving levodopa pharmacokinetics, European Journal of Pharmaceutics and Biopharmaceutics, 2025, 207, 114633
12. Cui Tang, Hui Wang, Lina Guo, Yimin Cui, Chan Zou, Jianming Hu, Hanyong Zhang, Guoping Yang*, Wenhu Zhou*, Multifunctional Nanomedicine for Targeted Atherosclerosis Therapy: Activating Plaque Clearance Cascade and Suppressing Inflammation, ACS Nano 2025, 19, 3, 3339–3361
13. Peng Liu+, Jia Guo+, Zuozhong Xie+, Yusheng Pan, Benliang Wei, Ying Peng, Shuo Hu, Jinsong Ding, Xiang Chen*, Juan Su*, Hong Liu*, Wenhu Zhou*, Co-Delivery of aPD-L1 and CD73 Inhibitor Using Calcium Phosphate Nanoparticles for Enhanced Melanoma Immunotherapy with Reduced Toxicity, Adv. Sci. 2024, 2410545
14. Jiahao Liu+, Qingnian Li+, Hanyu Tu+, Jie Feng, Xiaofei Fan, Ze Mi, Hongpei Han, Xiaoqian Ma, Qi Liang, Zheng Zhang, Hongshuai Hou*, Pengfei Rong*, Wenhu Zhou*, Bismuth/manganese-doped carbon dots in calcium phosphate matrix: Dynamic conformational nanoparticles enhancing tumor accumulation, deep penetration, and radiosensitivity, Chemical Engineering Journal, 2025, 504, 158683
15. Jieru Yang#, Huanmin Kang#, Yingyi Liu, Yan He*, Wenhu Zhou*, Harnessing Tumor Cell-Derived Exosomes for Immune Rejection Management in Corneal Transplantation, Adv. Sci. 2024, 2409207
16. Lingjiao Li, Chengyao Feng, Wenchao Zhang, Lin Qi, Binfeng Liu, Hua Wang, Chenbei Li, Zhihong Li, Chao Tu*, Wenhu Zhou*, Mitigation of Cisplatin-Induced Nephrotoxicity and Augmentation of Anticancer Potency via Tea Polyphenol Nanoparticles’ Codelivery of siRNA from CRISPR/Cas9 Screened Targets, ACS Appl. Mater. Interfaces 2024, 16, 44, 59721–59737
17. Jiahao Liu, Peng Liu, Junhong Duan, Qiongxuan Xie, Jie Feng, Hongpei Tan, Ze Mi, Ying Li, Yunjie Liao, Pengfei Rong*, Wenhu Zhou*, Xiang Gao*, Macrophages-mediated tumor accumulation and deep penetration of bismuth/manganese biomineralized nanoparticles for enhanced radiotherapy, Chinese Chemical Letters, 2024, 35, 109632
18. Yujie Fan, Yangqin Ou, Ting Xiao, Ziye Wei, LiLing Zhu, Chenghao Zhu, Yiran Ma, Shuangquan Qu*, Wenhu Zhou*, Coordination-Driven Nanomedicine Mitigates One-Lung Ventilation-Induced Lung Injury via Radicals Scavenging and Cell Pyroptosis Inhibition, Small 2024, 2401056
19. Ying Zhou, Yunxiao Ma, Jianwei Sheng, Yiran Ma, Jinsong Ding*, Wenhu Zhou*, Breaking Down Barriers in Drug Delivery by Stromal Remodeling Approaches in Pancreatic Cancer, Mol. Pharmaceutics 2024, 21, 8, 3764–3776
20. Aiping Huang, Qingnian Li, Xinyi Shi, Junyi Gao, Yiran Ma, Jinsong Ding, Surong Hua*, Wenhu Zhou*, An iron-containing nanomedicine for inducing deep tumor penetration and synergistic ferroptosis in enhanced pancreatic cancer therapy, Materials Today Bio, 2024, 27, 101132
21. Shan Lu, Ze Mi, Peng Liu, Jinsong Ding, Yiran Ma, Jieru Yang*, Pengfei Rong*, Wenhu Zhou*, Repolarizing neutrophils via MnO2 nanoparticle-activated STING pathway enhances Salmonella-mediated tumor immunotherapy, J Nanobiotechnol, 2024 22, 443
22. Youwei Xu, Zhonghui Zheng, Qing Lin, Jiaxin Huang, Jinsong Ding, Wenhu Zhou*, Structure Determination and 3D ED/MicroED-Guided Synthesis of a New (S)-Ibuprofen–l-phenylalanine Co-Crystal, Cryst. Growth Des. 2024, 24, 12, 4924–4929
23. Ming Zhou, Xiaoqin Yin, Bei Chen, Shuo Hu*, Wenhu Zhou*, A PET probe targeting polyamine transport system for precise tumor diagnosis and therapy, Asian Journal of Pharmaceutical Sciences, 2024, 19, 100924
24. Yingcai Meng, Jiaxin Huang, Jinsong Ding, Haiyan Zhou*, Yong Li*, Wenhu Zhou*, Mn-phenolic networks as synergistic carrier for STING agonists in tumor immunotherapy, Materials Today Bio, 2024, 26, 101018
25. Ying Wang, Yiyan Xu, Jiayu Song, Xueting Liu, Sijia Liu, Nan Yang, Le Wang, Yujie Liu, Yiwei Zhao, Wenhu Zhou*, Yunyan Zhang*, Tumor Cell-Targeting and Tumor Microenvironment–Responsive Nanoplatforms for the Multimodal Imaging-Guided Photodynamic/Photothermal/Chemodynamic Treatment of Cervical Cancer, Int J Nanomedicine. 2024;19:5837-5858
26. Hui Wang, Cui Tang, Yuxia Xiang, Chan Zou, Jianming Hu, Guoping Yang*, Wenhu Zhou*, Tea polyphenol-derived nanomedicine for targeted photothermal thrombolysis and inflammation suppression, J Nanobiotechnol, 2024, 22, 146
27. Jing Wang, Nuli Xie, Shan Lu, Bo Xiao, Yangqin Ou, Qingnian Li, Dexian Liu, Wenhu Zhou*, CpG and Rutin Co-Loaded DNA Tetrahedra for Targeted Therapy of Intracerebral Hemorrhage: Synergistic Hematoma Clearance and Neuroinflammation Inhibition, Advanced Functional Materials, 2024, 2403469.
28. Jiaojiao Zhu, Lanyuan Peng, Shah Jehan, Haiyang Wang, Xiang Chen, Shuang Zhao, and Wenhu Zhou*, Activable Photodynamic DNA Probe with an "AND" Logic Gate for Precision Skin Cancer Therapy, Research, 2024, DOI: 10.34133/research.0295
29. Xueming Xua, Yuanfeng Han, Jiali Deng, Shengfeng Wang, Shijie Zhuo, Kai Zhao,* Wenhu Zhou*, Repurposing disulfiram with CuET nanocrystals: Enhancing anti-pyroptotic effect through NLRP3 inflammasome inhibition for treating inflammatory bowel diseases, Acta Pharmaceutica Sinica B, 2024, 14 (6), 2698-2715
30. Xurui Gu, Kun Liu, Yixuan Deng, Bixiao Xiang, Lingyun Zhou, Wenjun Yin, Jiaxin Huang, Yingcai Meng, Dianke Li, Ruiman Que, Zhiyao Tang, Guangliang Zhou, Yifeng Wu, Yujie Huang, Wenhu Zhou*, Xiaocong Zuo*, A Renal-Targeted Gene Delivery System Derived from Spermidine for Arginase-2 Silencing and Synergistic Attenuation of Drug-Induced Acute Kidney Injury, Chemical Engineering Journal, 2024, 486, 150125
31. Yuanzheng Chen, Jiaojiao Zhu, Jinsong Ding, Wenhu Zhou, Recent progress of vaccines administration via microneedles for cancer immunotherapy, Chinese Chemical Letters, 2024, 35, 108706
32. Lina Guo, Jinsong Ding, Wenhu Zhou*, Harnessing bacteria for tumor therapy: Current advances and challenges, Chinese Chemical Letters, 2024, 35, 108557
33. Ying Peng, Peng Liu, Jinsong Ding, Wenhu Zhou*, Biomineralized nanomedicine for enhanced cancer therapy through in situ toxification and amplified Ca2+ overload, Chemical Engineering Journal, 2023, 475, 146277
34. Lina Guo, Jinsong Ding, Wenhu Zhou*, Converting bacteria into autologous tumor vaccine via surface biomineralization of calcium carbonate for enhanced immunotherapy, Acta Pharmaceutica Sinica B, 2023, 13(12): 5074–5090.
35. Jiaojiao Zhu+, Tiao Wen+, Shuangquan Qu, Qingnian Li, Biwu Liu, and Wenhu Zhou*, G-quadruplex/Hemin DNAzyme-Functionalized Silver Nanoclusters with Synergistic Anti-Bacterial and Wound Healing Capabilities for Infected Wound Management, Small, 2023, 2307220
36. Lina Guo, Hao Chen, Jinsong Ding, Pengfei Rong, Ming Sun, Wenhu Zhou*, Surface engineering Salmonella with pH-responsive polyserotonin and self-activated DNAzyme for better microbial therapy of tumor, Exploration 2023, 00, 20230017
37. Cui Tang, Hui Wang, Lina Guo, Chan Zou, Jianming Hu, Hanyong Zhang, Wenhu Zhou*, and Guoping Yang*, CpG Conjugated Silver Nanoparticle as Multifunctional Nanomedicine to Promote Macrophage Efferocytosis and Re-polarization for Atherosclerosis Therapy, ACS Appl. Mater. Interfaces 2023, 15, 45, 52162–52179
38. Xiangcheng Zhao, Nuli Xie, Hailong Zhang, Wenhu Zhou*, and Jinsong Ding*, Bacterial Drug Delivery Systems for Cancer Therapy: “Why” and “How”, Pharmaceutics, 2023, 15(9), 2214
39. Hao Chen, Lina Guo, Jinsong Ding, Wenhu Zhou*, Yan Qi*, A General and Efficient Strategy for Gene Delivery Based on Tea Polyphenols Intercalation and Self-Polymerization, Advanced Science, 2023, 2302620.
40. Zhang, Hui; Wang, Laifa; Zhu, Bi; Yang, Yongping; Cai, Chuanhai; Wang, Xueqin; Deng, Ling; He, Binsheng; Cui, Yanhui*, Wenhu Zhou*, A comparative study of the neuroprotective effects of dl-3-n-butylphthalide and edaravone dexborneol on cerebral ischemic stroke rats, European Journal of Pharmacology, 2023, 951, 15, 175801
41. Liping Dong, Jinsong Ding, Lemei Zhu, Yujun Liu, Xiang Gao*, Wenhu Zhou*, Copper carbonate nanoparticles as an effective biomineralized carrier to load macromolecular drugs for multimodal therapy, Chinese Chemical Letters, 2023, 34, 108192
42. Yingcai Meng, Jiaxin Huang, Jinsong Ding, Bohua Yan, Yong Li*, Xiang Gao*, Wenhu Zhou*, Poly-thymine DNA templated MnO2 biomineralization as a high-affinity anchoring enabling tumor targeting delivery, Journal of Colloid and Interface Science, 2023, 637, 441-452
43. Shu Huang, Jun Yuan, Yong Xie, Kai Qing, Zeya Shi, Guanyu Chen, Jie Gao, Haoxiang Tan, Wenhu Zhou*, Targeting nano-regulator based on metal–organic frameworks for enhanced immunotherapy of bone metastatic prostate cancer, Cancer Nanotechnology, 2023, 14, 43
44. Aiping Huang, Wenhu Zhou*, Mn-based cGAS-STING activation for tumor therapy. Chin J Cancer Res 2023; 35(1):19-43.
45. Hui Zhang†, Laifa Wang†, Yongping Yang, Chuanhai Cai, Xueqin Wang, Ling Deng, Binsheng He, Wenhu Zhou* and Yanhui Cui*, DL-3-n-butylphthalide (NBP) alleviates poststroke cognitive impairment (PSCI) by suppressing neuroinflammation and oxidative stress, Frontiers in Pharmacology, 2023, DOI: 10.3389/fphar.2022.987293
46. Lingjiao Li†, Shengmei Wang† and Wenhu Zhou*, Balance Cell Apoptosis and Pyroptosis of Caspase-3-Activating Chemotherapy for Better Antitumor Therapy, Cancers, 2023, 15, 26
47. Jia Guo+, Peng Liu+, Benliang Wei+, Ying Peng, Jinsong Ding, Hailun Zhang, Guanxiong Zhang, Juan Su*, Hong Liu*, Wenhu Zhou*, Xiang Chen*, Reversing the Negative Effect of Adenosine A1 Receptor-Targeted Immunometabolism Modulation on Melanoma by a Co-delivery Nanomedicine for Self-activation of anti-PD-L1 DNAzyme, Nano Today, 2023, 48, 101722
48. Xiaoxiong Xiao, Min Chen, Yuchen Zhang, Liang Li, Ying Peng, Junyu Li* and Wenhu Zhou*, Hemin-incorporating DNA nanozyme enabling catalytic oxygenation and GSH depletion for enhanced photodynamic therapy and synergistic tumor ferroptosis, Journal of Nanobiotechnology, 2022, 20:410
49. Jiaojiao Zhu+, Ruimin Chang+, Benliang Wei, Yao Fu, Xiang Chen*, Hong Liu*, and Wenhu Zhou*, Photothermal Nano-Vaccine Promoting Antigen Presentation and Dendritic Cells Infiltration for Enhanced Immunotherapy of Melanoma via Transdermal Microneedles Delivery, Research, 2022, DOI：10.34133/2022/9816272
50. Jiahao Liu#, Lina Guo#, Ze Mi, Liu Zhenguo, Pengfei Rong* and Wenhu Zhou*, Vascular Bursts-Mediated Tumor Accumulation and Deep Penetration of Spherical Nucleic Acids for Synergistic Radio-Immunotherapy, Journal of Controlled Release, 2022, 348, 1050-1065
51. Ze Mi#, Qing Yao#, Yan Qi, Jinhai Zheng, Jiahao Liu, Zhenguo Liu, Hongpei Tan, Xiaoqian Ma, Wenhu Zhou*, Pengfei Rong*, Salmonella-Mediated Blood-Brain Barrier Penetration, Tumor Homing and Tumor Microenvironment Regulation for Enhanced Chemo/Bacterial Glioma Therapy, Acta Pharmaceutica Sinica B, 2023, 819-833
52. Shengmei Wang1,4#, Xuanjun Liu1,2#, Minghua Yang3, Linqi Ouyang4, Jinsong Ding2, Shengfeng Wang*1,2,3, and Wenhu Zhou*, Non-cytotoxic Nanoparticles Re-educating Macrophages Achieving both Innate and Adaptive Immune Responses for Tumor Therapy, Asian Journal of Pharmaceutical Sciences, 2022, 17 (4) 557-570
53. Yingcai Meng, Jiaojiao Zhu, Jinsong Ding, Wenhu Zhou*, Polyserotonin as a Versatile Coating with pH-responsive Degradation for Anti-tumor Therapy, Chem. Commun., 2022,58, 6713-6716
54. Jiali Deng+, Rui Wang+, Jinsong Ding* and Wenhu Zhou*, Macrophages-Regulating Nanomedicines for Sepsis Therapy, Chinese Chemical Letters, 2023,34, 107588
55. Lina Guo+, Shenghui Zhong+, Peng Liu, Man Guo, Jinsong Ding and Wenhu Zhou*, Radicals Scavenging MOFs Enabling Targeting Delivery of siRNA for Rheumatoid Arthritis Therapy, Small, 2022, 27, 2202604
56. Hanane Aliouat#, Ying Peng#, Zoya Waseem, Shengfeng Wang, and Wenhu Zhou*, Pure DNA scaffolded Drug Delivery Systems for Cancer Therapy, Biomaterials, 2022, 285, 121532
57. Mengzhen Yu#, Yanwen Zhang#, Meirong Fang, Shah Jehan* and Wenhu Zhou*, Current Advances of Nanomedicines Delivering Arsenic Trioxide for Enhanced Tumor Therapy, Pharmaceutics, 2022, 14(4), 743
58. Qin Ouyang#, Kai Liu#, Qubo Zhu#, Huiyin Deng, Yuan Le, Wen Ouyang, Xiaoxin Yan, Wenhu Zhou*, Jianbin Tong*, Brain-Penetration and Neuron-Targeting DNA Nanoflowers Co-Delivering miR-124 and Rutin for Synergistic Therapy of Alzheimer's Disease, Small, 2022, 2107534
59. Weidong Sun#, Yiyan Xu#, Ye Yao, Jie Yue, Zhen Wu, Haocheng Li, Guanghui Shen, Yan Liao, Haiyang Wang*, and Wenhu Zhou*, Self-oxygenation Mesoporous MnO2 Nanoparticles with Ultra-High Drug Loading Capacity for targeted Arteriosclerosis Therapy, Journal of Nanobiotechnology, 2022, 20, 88
60. Yuan Chen#, Ruiheng Luo#, Jing Li#, Shengfeng Wang, Jinsong Ding, Kai Zhao*, Ben Lu* and Wenhu Zhou*, Intrinsic Radical Species Scavenging Activities of Tea Polyphenols Nanoparticles Blocks Pyroptosis in Endotoxin-Induced Sepsis, ACS Nano, 2022, 16, 2429-2441
61. Peng Liu+, Ying Peng, Jinsong Ding and Wenhu Zhou*, Fenton Metal Nanomedicines for Imaging-guided Combinatorial Chemodynamic Therapy against Cancer, Asian Journal of Pharmaceutical Sciences, 2022, 17, 177-192
62. Yuejia Song, Yaqian Huang, Fang Zhou, Jinsong Ding*, Wenhu Zhou*, Macrophage-targeted nanomedicine for chronic diseases immunotherapy, Chinese Chemical Letters, 2022, 33, 597-612
63. Jiaojiao Zhu, Man Guo, Yanhui Cui, Yingcai Meng, Jinsong Ding, Wenbin Zeng, and Wenhu Zhou*, Surface Coating of Pulmonary siRNA Delivery Vectors Enabling Mucus Penetration, Cell Targeting, and Intracellular Radical Scavenging for Enhanced Acute Lung Injury Therapy, ACS Appl. Mater. Interfaces 2022, 14, 4, 5090–5100
64. Shah Jehan, Jiaxin Huang, Umar Farooq, Irum Basheer and Wenhu Zhou*, Combinatorial effect of thymoquinone with chemo agents for tumor therapy, Phytomedicine, 2022, 98, 153936
65. Pingping Bing, Wenhu Zhou* and Songwen Tan*, Study on the Mechanism of Astragalus Polysaccharide in Treating Pulmonary Fibrosis Based on “Drug-Target-Pathway” Network, Front. Pharmacol.,2022, 13:865065.
66. Peng Liu+, Xinyi Shi+, Ying Peng, Jianming, Hu, Jinsong Ding and Wenhu Zhou*, Anti-PD-L1 DNAzyme Loaded Photothermal Mn2+/Fe3+ Hybrid Metal-Phenolic Networks for Cyclically Amplified Tumor Ferroptosis-Immunotherapy, Advanced Healthcare Materials, 2022, 11, 2102315
67. Shengmei Wang, Xuanjun Liu, Shengfeng Wang, Linqi Ouyang, Hui Li, Jinsong Ding, Guiming Deng*, and Wenhu Zhou*, Imatinib co-loaded targeted realgar nanocrystal for synergistic therapy of chronic myeloid leukemia, Journal of Controlled Release, 2021, 338, 190-200
68. Yang Zeng, Haiyan Zhou, Jinsong Ding, and Wenhu Zhou*, Cell membrane inspired nano-shell enabling long-acting Glucose Oxidase for Melanoma starvation therapy via microneedles-based percutaneous delivery, Theranostics, 2021; 11:8270-8282
69. Peng Liu, Yanbin Zhou, Xinyi Shi, Yu Yuan, Ying Peng, Jinsong Ding, Yong Li*, and Wenhu Zhou*, A Cyclic Nano-reactor Achieving Enhanced Photodynamic Tumor Therapy by Reversing Multiple Resistances, J. Nanobiotechnol., 2021, 19, 149
70. Peng Liu, Ying Peng, Yanbin Zhou, Xinyi Shi, Qingnian Li, Jinsong Ding, Yang Gao,* and Wenhu Zhou*, Rapamycin as a “One-Stone-Three-Birds” Agent for Cooperatively Enhanced Phototherapies Against Metastatic Breast Cancer, ACS Appl. Mater. Interfaces, 2021, 13, 22, 25674–25684
71. Peng Liu, Xinyi Shi, Shenghui Zhong, Ying Peng, Yan Qi, Jinsong Ding, Wenhu Zhou*, Metal-phenolic networks for cancer theranostics, Biomater. Sci., 2021,9, 2825-2849
72. Shenghui Zhong, Peng Liu, Jinsong Ding* and Wenhu Zhou*, Hyaluronic Acid-Coated MTX-PEI Nanoparticles for Targeted Rheumatoid Arthritis Therapy, Crystals, 2021, 11(4), 321-334
73. Man Guo, Yingcai Meng, Xiaoqun Qin*, and Wenhu Zhou*, Dopamine-Grafted Hyaluronic Acid Coated Hyperbranched Poly(β-Amino Esters)/DNA Nano-Complexes for Enhanced Gene Delivery and Biosafety, Crystals, 2021, 11(4), 347-360
74. Yang Xi, Xin Xie, Ying Peng, Peng Liu, Jinsong Ding* and Wenhu Zhou*, DNAzyme-adsorbed polydopamine@MnO2 core–shell nanocomposites for enhanced photothermal therapy via the self-activated suppression of heat shock protein 70, Nanoscale, 2021, 13, 5125-5135
75. Peng Liu, Xin Xie, Miao Liu, Shuo Hu, Jinsong Ding, Wenhu Zhou*, A Smart MnO2 Doped Graphene Oxide Nanosheet for Enhanced Chemo-Photodynamic Combinatorial Therapy via Simultaneous Oxygenation and Glutathione Depletion, Acta Pharmaceutica Sinica B, 2021, 11, 823-834
76. Yihua Yang, Lina Guo, Zhe Wang, Peng Liu, Xuanjun Liu, Jinsong Ding, Wenhu Zhou*, Targeted silver nanoparticles for rheumatoid arthritis therapy via macrophage apoptosis and Re-polarization, Biomaterials, 2021, 264, 120390
77. Lina Guo, Yang Chen, Ting Wang, Yu Yuan, Yihua Yang, Xiaoli Luo, Shuo Hu, Jinsong Ding* and Wenhu Zhou*, Rational design of metal-organic frameworks to deliver methotrexate for targeted rheumatoid arthritis therapy, Journal of Controlled Release, 2021, 330, 119-131
78. Ze Mi#, Lina Guo#, Peng Liu#, Yan Qi, Zhichao Feng, Jiahao Liu, Zhenhu He, Xiao Yang, Shengnan Jiang, Jianzhen Wu, Jinsong Ding, Wenhu Zhou*, and Pengfei Rong*, “Trojan Horse” Salmonella Enabling Tumor Homing of Silver Nanoparticles via Neutrophil Infiltration for Synergistic Tumor Therapy and Enhanced Biosafety, Nano letters, 2021, 21, 1, 414–423
79. Yingcai Meng, Yuan Chen, Jiaojiao Zhu, Yan Qi, Jinsong Ding, Wenhu Zhou*, Polarity Control of DNA Adsorption Enabling Surface Functionalization of CuO Nanozyme for Targeted Tumor Therapy, Materials Horizons, 2021, 8, 972-986
80. Mengchang Xu, Fenglin Liu, Wenhu Zhou*, Binsheng He, Songwen Tan*, Preparation and preliminary quality evaluation of aspirin/L-glutamate compound pellets, Journal of Materials Science: Materials in Medicine, 2021, 32:116
81. Mengchang Xu, Wenhu Zhou*, Xuncai Chen, Ying Zhou, Binsheng He, Songwen Tan*, Analysis of the biodegradation performance and biofouling in a halophilic MBBR-MBR to improve the treatment of disinfected saline wastewater, Chemosphere, 2021, 269, 128716
82. Hanyong Zhang, Wenhu Zhou*, Xuehui Zhan, Zhenxing Chi, Weiguo Li, Binsheng He, Songwen Tan*, Biodegradation performance and biofouling control of a halophilic biocarriers-MBR in saline pharmaceutical (ampicillin-containing) wastewater treatment, Chemosphere, 2021, 263, 127949
83. Taoli Sun, Wenqun Li, Xiaoliang Tong, Xinyi Liu, Wenhu Zhou*, Xanthohumol attenuates isoprenaline-induced cardiac hypertrophy and fibrosis through regulating PTEN/AKT/mTOR pathway, European Journal of Pharmacology, 2021, 891, 15, 173690
84. Peng Liu, Xuanjun Liu, Yan Cheng, Shenghui Zhong, Xinyi Shi, Shengfeng Wang, Jinsong Ding, Wenhu Zhou*, Core-Shell Nanosystems for Self-Activated Drug-Gene Combinations against Triple-Negative Breast Cancer, ACS Appl. Mater. Interfaces, 2020, 48, 53654-53664
85. Yunbo Nie, Dan Li, Ying Peng, Shengfeng Wang, Jinsong Ding* and Wenhu Zhou*, Metal Organic Framework Coated MnO2 Nanosheets Delivering Doxorubicin and Self-activated DNAzyme for Chemo-gene Combinatorial Treatment of Cancer, International Journal of Pharmaceutics, 2020, 585, 1195
86. Ying Peng, Peng Liu, Yingcai Meng, Jinsong Ding* and Wenhu Zhou*, Nanoscale Copper(II)-Diethyldithiocarbamate Coordination Polymer as Drug Self-delivery System for Highly Robust and Specific Cancer Therapy, Molecular Pharmaceutics, 2020, 8, 2864-2873
87. Miao Liu, Ying Peng, Yunbo Nie, Peng Liu, Shuo Hu, Jinsong Ding* and Wenhu Zhou*, Co-delivery of doxorubicin and DNAzyme using ZnO@polydopamine core-shell nanocomposites for chemo/gene/photothermal therapy, Acta Biomaterialia, 2020, 110, 242-253
88. Peng Liu, Xin Xie, Xinyi Shi, Ying Peng, Jinsong Ding and Wenhu Zhou*, Oxygen-Self-Supplying and HIF-1α-Inhibiting Core−Shell Nanosystem for Hypoxia-Resistant Photodynamic Therapy, ACS Appl. Mater. Interfaces 2019, 11, 48261−48270
89. Liang Li, Yingcai Meng, Ling Li, Shengfeng Wang, Jinsong Ding* and Wenhu Zhou*, A Tetrahedral DNA Nanoflare for Fluorometric Determination of Nucleic Acids and Imaging of MicroRNA Using Toehold Strands, Microchimica Acta, 2019, 186, 824
90. Yang Yihua, Wang Zhe, Peng Ying, Jinsong Ding* and Wenhu Zhou*, A Smart pH-Sensitive Delivery System for Enhanced Anticancer Efficacy via Paclitaxel Endosomal Escape, Frontiers in Pharmacology, 2019, DOI: 10.3389/fphar.2019.00010
91. Xiaoli Luo, Xin Xie, Yingcai Meng, Taoli Sun, Jinsong Ding* and Wenhu Zhou*, Ligands dissociation induced gold nanoparticles aggregation for colorimetric Al3+ detection, Analytica Chimica Acta, 2019, 1087, 9, 76-85
92. Shengfeng Wang, Jinsong Ding* and Wenhu Zhou*, An aptamer-tethered, DNAzyme-embedded molecular beacon for simultaneous detection and regulation of tumor-related genes in living cells, Analyst, 2019, 144, 5098-5107
93. Liu Peng, Guo Binbin, Wang Shengfeng, Jinsong Ding* and Wenhu Zhou*, A thermo-responsive and self-healing liposome-in-hydrogel system as an antitubercular drug carrier for localized bone tuberculosis therapy, International Journal of Pharmaceutics, 2019, 558, 101-109
94. Yang Chen, Cejun Yang, Juan Mao, Haigang Li, Ying, Jinsong Ding* and Wenhu Zhou*, Spermine Modified Polymeric Micelles with pH-Sensitive Drug Release for Targeted and Enhanced Antitumor Therapy, RSC Advances, 2019, 9, 11026-11037
95. Yingcai Meng, Peng Liu, Wenhu Zhou*, Jinsong Ding*, Juewen Liu, Bioorthogonal DNA Adsorption on Polydopamine Nanoparticles Mediated by Metal Coordination for Highly Robust Sensing in Serum and Living Cells, ACS Nano, 2018, 12, 9070-9080
96. Peng Liu, Shengfeng Wang, Xuanjun Liu, Jinsong Ding* and Wenhu Zhou*, Platinated graphene oxide: A nanoplatform for efficient gene-chemo combination cancer therapy, European journal of pharmaceutical sciences, 2018, 121, 319-329
97. Binbin Guo, Yuqiao Zhang, Shengfeng Wang, Jinsong Ding and Wenhu Zhou*, The pharmacokinetics of morphine and codeine in human plasma and urine after oral administration of Qiangli Pipa Syrup, Journal of forensic science, 2018, 63, 1221-1228
98. Shengfeng Wang, Chuantong Zhao, Peng Liu, Zhe Wang, Jinsong Ding* and Wenhu Zhou*, Facile construction of dual-targeting delivery system by using lipid capped polymer nanoparticles for anti-glioma therapy. RSC Advances, 2018, 8, 444–453
99. Wenhu Zhou* and Juewen Liu*, "Multi-metal-dependent nucleic acid enzymes", Metallomics, 2018, 10, 30-48
100. Wenhu Zhou, Jinsong Ding and Juewen Liu*, "Splitting a DNAzyme enabling Na+-dependent FRET signal from the embedded aptamer", Organic & Biomolecular Chemistry, 2017, 15, 6959-6966
101. Wenhu Zhou, Runjhun Saran, Jinsong Ding and Juewen Liu*, "Two Completely Different Mechanisms for Highly Specific Na+ Recognition by DNAzymes", ChemBioChem, 2017, 18, 1828-1835
102. Wenhu Zhou, Runjhun Saran and Juewen Liu*, "Metal Sensing by DNA", Chemical Reviews, 2017, 117, 8272–8325
103. Wenhu Zhou, Runjhun Saran, Po-Jung Jimmy Huang, Jinsong Ding and Juewen Liu*, "An Exceptionally Selective DNA Cooperatively Binding Two Ca2+ Ions", ChemBioChem, 2017, 18, 518-522.
104. Wenhu Zhou, Jinsong Ding and Juewen Liu*, "Theranostic DNAzymes", Theranostics, 2017, 7, 1010-1025
105. Wenhu Zhou, Jinsong Ding and Juewen Liu*, "2-Aminopurine-modified DNA homopolymers for robust and sensitive detection of mercury and silver", Biosensors & Bioelectronics, 2017, 87, 171-177
106. Wenhu Zhou, Jinsong Ding and Juewen Liu*, "A highly specific sodium aptamer probed by 2-aminopurine for robust Na+ sensing", Nucleic Acids Research, 2016, 44, 10377-10385
107. Wenhu Zhou, Tianmeng Yu, Mahsa Vazin, Jinsong Ding and Juewen Liu*, "Cr3+ Binding to DNA Backbone Phosphate and Bases: Slow Ligand Exchange Rates and Metal Hydrolysis", Inorganic Chemistry, 2016, 55, 8193–8200
108. Wenhu Zhou, Jinsong Ding and Juewen Liu*, "A Selective Na+ Aptamer Dissected by Sensitized Tb3+ Luminescence", ChemBioChem, 2016, 17, 1563–1570
109. Wenhu Zhou, Mahsa Vazin, Tianmeng Yu Jinsong Ding and Juewen Liu*, "In Vitro Selection of Chromium-Dependent DNAzymes for Sensing Cr(III) and Cr(VI)", Chemistry, a European Journal, 2016, 22, 9835-9840
110. Wenhu Zhou, Yupei Zhang, Jinsong Ding* and Juewen Liu*, "In Vitro Selection in Serum: RNA-Cleaving DNAzymes for Measuring Ca2+ and Mg2+", ACS Sensors, 2016, 1, 600-606
111. Wenhu Zhou, Jinsong Ding and Juewen Liu*, "An Efficient Lanthanide-Dependent DNAzyme Cleaving 2’-5’ Linked RNA", ChemBioChem, 2016, 17, 890-894
112. Wenhu Zhou, Runjhun Saran, Qingyun Chen, Jinsong Ding and Juewen Liu*, "A New Na+-Dependent RNA-Cleaving DNAzyme with over 1000-fold Rate Acceleration by Ethanol", ChemBioChem, 2016, 17, 159-163
113. Wenhu Zhou, Yupei Zhang, Po-Jung Jimmy Huang, Jinsong Ding, and Juewen Liu*, "A DNAzyme requiring two different metal ions at two distinct sites", Nucleic Acids Research, 2016, 44, 354-363
114. Wenhu Zhou, Jinsong Ding* and Juewen Liu*, "A platinum shell for ultraslow ligand exchange: unmodified DNA adsorbing more stably on platinum than thiol and dithiol on gold", Chemical Communications, 2015, 51, 12084-12087
115. Wenhu Zhou, Qingyun Chen, Po-Jung Jimmy Huang, Jinsong Ding* and Juewen Liu*, "DNAzyme Hybridization, Cleavage, Degradation and Sensing in Undiluted Human Blood Serum", Analytical Chemistry, 2015, 87, 4001–4007
116. Wenhu Zhou, Feng Wang, Jinsong Ding* and Juewen Liu*, "Tandem Phosphorothioate Modifications for DNA Adsorption Strength and Polarity Control on Gold Nanoparticles", ACS Applied Materials & Interfaces, 2014, 6, 14795-14800
117. Wenhu Zhou, Po-Jung Jimmy Huang, Jinsong Ding* and Juewen Liu*, "Aptamer-based biosensors for biomedical diagnostics", Analyst, 2014, 139, 2627-2640
118. Wenhu Zhou, Yanbin Zhou, Jianping Wu, Zhenbao Liu, Huanzhe Zhao, Juewen Liu*, and Jinsong Ding*. "Aptamer-nanoparticle bioconjugates enhance Intracellular delivery of vinorelbine to breast cancer cells", Journal of Drug Targeting, 2014, 22(1): 57-66
119. Wenhu Zhou, Shiying He, Yijun Yang, Dan Jian, Xiang Chen*, and Jinsong Ding*," Formulation, characterization and clinical evaluation of propranolol hydrochloride gel for transdermal treatment of superficial infantile hemangioma”, Drug development and industrial pharmacy, 2015, 41 (7), 1109-1119
